Cagliari enter the September 7 Serie A fixture at the Sardegna Arena on the back of a strong opening-weekend 1-0 win at Parma, where new signings including Alessandro Romano contributed and the side created multiple high-quality chances. Lecce also claimed a clean-sheet victory on the road against Venezia, continuing their pattern of compact, low-scoring performances. Historical head-to-head data shows tight contests with Cagliari holding a modest home edge, though both clubs have similar mid-to-lower table profiles and limited attacking firepower early in the campaign. Minor squad concerns for Cagliari center on Yael Trepy’s ongoing recovery and long-term absentee Riyad Idrissi, while Lecce’s Medon Berisha edges closer to full fitness. These factors underpin the market’s slight lean toward a Cagliari win or draw as the most probable outcomes.