Relegation in the 2026 Liga AUF Uruguaya is decided by the lowest three averages of points per game across the combined 2025 and 2026 seasons, giving established sides with weak prior campaigns a significant disadvantage. Progreso sits at the bottom of the table with the weakest average near 0.95, followed closely by Danubio, while teams like Cerro and Montevideo Wanderers occupy the next positions and remain vulnerable. Newly promoted sides such as Albion, Central Español, and Deportivo Maldonado carry only current-season points, leaving them exposed if results falter in the ongoing Clausura. Recent form, goal difference, and head-to-head results in the final weeks will directly shift these averages and determine which clubs drop to the Segunda División.